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| 05.16.23 | Ozempic and Wegovy boost cancer-fighting cells; Human genome map gets major upgrade

Questex sent this email to their subscribers on May 16, 2023.

Manufacturing stem cells in microgravity?

This Week

May 16, 2023

Ozempic and Wegovy have taken over obesity treatment. Can they help with cancer too?


Humanity's guide to the human genome just got a major upgrade


Stem cell manufacturing in microgravity: Scientists will test growing iPSCs on Axiom 2


Human brain organoids in mice give first glimpse of microglia dysfunction in autism

 

Featured

Ozempic and Wegovy have taken over obesity treatment. Can they help with cancer, too?

Novo Nordisk’s Ozempic and Wegovy may have benefits beyond helping patients shed pounds: They appear to reverse the impairments in cancer-fighting natural killer cells seen in people with obesity, independent of weight loss.
 

Top Stories

Humanity's guide to the human genome just got a major upgrade

Scientists have released the first draft of the human pangenome reference, a new blueprint of human DNA built on data from a much more diverse cohort than the original.

Is space the place for stem cell manufacturing? Scientists will soon test that on the ISS

The world’s second-ever private astronaut mission to the International Space Station will ferry a first-of-its-kind experiment that will test whether scientists can create induced pluripotent stem cells in microgravity.

Human brain organoids in mice give first glimpse of microglia dysfunction in autism

Scientists have once again implanted human-derived organoids into mouse brains, in this case to study the brain’s immune cells in-depth for the first time.

BioNTech swiftly axes oral mRNA vaccine project after tech flunks early test

BioNTech has swiftly rejected an oral mRNA delivery technology. Barely one year after signing up to work with Matinas BioPharma, BioNTech found an initial mouse study failed to show preclinical activity—leading it to join Gilead on the list of companies to dump the biotech in recent months.

NYBC Ventures launches with $50M for blood and cell therapies

NYBC Ventures has unveiled as one of the first venture funds to focus solely on advancing new blood and cell-based therapies, with $50 million in hand from the New York Blood Center.

Envivo's smart capsule opens a window on gut health

Want to know what’s going on across the length of your gastrointestinal tract? Swallowing a smart capsule device developed by Envivo Bio could give you the answer, according to a new study.

Liver disease misinformation rampant on TikTok: study

Around 40% of liver disease posts on social media site TikTok contain misinformation in a worrying trend doctors want to reverse.

We want your stories: Biopharma's collective memory of COVID—in photographs

Fierce Pharma is asking you, the dedicated employees working in the biopharma industry, to tell your stories of the pandemic—in photographs.
 
Fierce podcasts

Don't miss an episode

1 V d el o 2

'The Top Line': The final installment of a series on Narcan, plus this week's headlines

This week on "The Top Line," we're concluding our miniseries on Narcan the nasal spray. It is the first naloxone product to be approved for use without a prescription.
 

Resources

Whitepaper

ChatGPT in Drug Discovery: Rise of Large Language Models

ChatGPT shows promise in drug discovery for information extraction, scientific text authoring, hypothesis prediction, and chemical entity prediction. This whitepaper explores its potential to streamline research, delving into its technology, applications, and limitations.
Whitepaper

Discovering High-Affinity, Functional Anti-GLP-1R Antibodies

Learn how a GPCR-focused library with a cell-based biopanning strategy led to the discovery of 13 high-affinity and selective anti-GLP-1R antibodies with highly developable therapeutic properties.
eBook

Decentralized Clinical Trials: The Complete Guide for 2023

Discover a game-changing approach to clinical research with Hybrid and Decentralized Clinical Trials (DCTs). Learn about the benefits, challenges, and key elements for success.
Research

How Lilly’s Legal and Library Services Empower Teams Across the Drug Development Pipeline

What role do the Library and Legal teams play in the drug development pipeline at Lilly? An import one – find out how.
Whitepaper

Medical Affairs Metamorphosis VI: The Changing Face of Stakeholder Engagement

This paper focuses on stakeholder engagement and how Medical Affairs teams’ responsibilities, goals, tools, and techniques are changing.
Research

Maximizing Clinical Trial Success

Strategies for Optimal Site Selection and Feasibility Research in Novel Therapies and Geographies
Whitepaper

eConsent: Flexible Consent Through Enabling Technologies

How can eConsent provide a more flexible approach to informed consent?

 

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Brand Logo W BIOTECH RESEARCH A message from altasciences Webinar: Species Selection Criteria for Your Toxicology Program. Watch Now. N ALTASCIENCES THIS WEEK May 16, 2023 Ozempic and Wegovy have taken over obesity treatment. Can they help with cancer too? ---------------------------------------------------------------------------------------------------------------------------------- Humanity's guide to the human genome just got a major upgrade ---------------------------------------------------------------------------------------------------------------------------------- Stem cell manufacturing in microgravity: Scientists will test growing iPSCs on Axiom 2 ---------------------------------------------------------------------------------------------------------------------------------- Human brain organoids in mice give first glimpse of microglia dysfunction in autism A message from olonspa Global leader in the development and productionof API for COMO and Generics FEATURED OZEMPIC AND WEGOVY HAVE TAKEN OVER OBESITY TREATMENT. CAN THEY HELP WITH CANCER, TOO? By Helen Floersh Novo Nordisk’s Ozempic and Wegovy may have benefits beyond helping patients shed pounds: They appear to reverse the impairments in cancer-fighting natural killer cells seen in people with obesity, independent of weight loss. TOP STORIES HUMANITY'S GUIDE TO THE HUMAN GENOME JUST GOT A MAJOR UPGRADE By Helen Floersh Scientists have released the first draft of the human pangenome reference, a new blueprint of human DNA built on data from a much more diverse cohort than the original. IS SPACE THE PLACE FOR STEM CELL MANUFACTURING? SCIENTISTS WILL SOON TEST THAT ON THE ISS By Helen Floersh The world’s second-ever private astronaut mission to the International Space Station will ferry a first-of-its-kind experiment that will test whether scientists can create induced pluripotent stem cells in microgravity. HUMAN BRAIN ORGANOIDS IN MICE GIVE FIRST GLIMPSE OF MICROGLIA DYSFUNCTION IN AUTISM By Helen Floersh Scientists have once again implanted human-derived organoids into mouse brains, in this case to study the brain’s immune cells in-depth for the first time. A message from Fierce Clinical Summit FIERCE CLINICAL SUMMIT September 26-28, 2023 | Philadelphia, PA Explore how the next wave of innovation in decentralized trials is focused on driving adoption through an investment and focus on building processes, and education and training programs, to make the model work for both organizations and patients.  Secure your pass today and take advantage of the Super Early Bird Rate! FIERCE Clinical Summit BIONTECH SWIFTLY AXES ORAL MRNA VACCINE PROJECT AFTER TECH FLUNKS EARLY TEST By Nick Paul Taylor BioNTech has swiftly rejected an oral mRNA delivery technology. Barely one year after signing up to work with Matinas BioPharma, BioNTech found an initial mouse study failed to show preclinical activity—leading it to join Gilead on the list of companies to dump the biotech in recent months. NYBC VENTURES LAUNCHES WITH $50M FOR BLOOD AND CELL THERAPIES By Gabrielle Masson NYBC Ventures has unveiled as one of the first venture funds to focus solely on advancing new blood and cell-based therapies, with $50 million in hand from the New York Blood Center. ENVIVO'S SMART CAPSULE OPENS A WINDOW ON GUT HEALTH By Phil Taylor Want to know what’s going on across the length of your gastrointestinal tract? Swallowing a smart capsule device developed by Envivo Bio could give you the answer, according to a new study. LIVER DISEASE MISINFORMATION RAMPANT ON TIKTOK: STUDY By Ben Adams Around 40% of liver disease posts on social media site TikTok contain misinformation in a worrying trend doctors want to reverse. WE WANT YOUR STORIES: BIOPHARMA'S COLLECTIVE MEMORY OF COVID—IN PHOTOGRAPHS By Angus Liu Fierce Pharma is asking you, the dedicated employees working in the biopharma industry, to tell your stories of the pandemic—in photographs. Fierce podcasts DON'T MISS AN EPISODE 1 V d el o 2 'THE TOP LINE': THE FINAL INSTALLMENT OF A SERIES ON NARCAN, PLUS THIS WEEK'S HEADLINES This week on "The Top Line," we're concluding our miniseries on Narcan the nasal spray. It is the first naloxone product to be approved for use without a prescription. * NARCANGoriy 3 NASALSPRleg' 'THE TOP LINE': PART 2 OF A SERIES ON NARCAN 'PODNOSIS': MEDICAID REDETERMINATION, TACKLING COLORECTAL CANCER A message from IDT Biologika WEBINAR: THE FUTURE OF VACCINE DEVELOPMENT AND MANUFACTURING – THE BENEFITS OF COMBINING IDT BIOLOGIKA’S MVA TECHNOLOGY PLATFORM WITH INNOVATIVE ANALYTICAL METHODS Thursday, May 25, 2023 | 10am ET / 7:00 PT Join the webinar and discover our MVA technology platform and explore the advantages for development and manufacturing of multiple vaccines and cell and gene therapeutics. Register now.  DT BIOLOGIKA RESOURCES Whitepaper CHATGPT IN DRUG DISCOVERY: RISE OF LARGE LANGUAGE MODELS ChatGPT shows promise in drug discovery for information extraction, scientific text authoring, hypothesis prediction, and chemical entity prediction. This whitepaper explores its potential to streamline research, delving into its technology, applications, and limitations. Sponsored by: Elucidata Corp., Cloud SAAS in Life Sciences R&D Whitepaper DISCOVERING HIGH-AFFINITY, FUNCTIONAL ANTI-GLP-1R ANTIBODIES Learn how a GPCR-focused library with a cell-based biopanning strategy led to the discovery of 13 high-affinity and selective anti-GLP-1R antibodies with highly developable therapeutic properties. Sponsored by: Twist Bioscience eBook DECENTRALIZED CLINICAL TRIALS: THE COMPLETE GUIDE FOR 2023 Discover a game-changing approach to clinical research with Hybrid and Decentralized Clinical Trials (DCTs). Learn about the benefits, challenges, and key elements for success. Sponsored by: EvidentIQ Research HOW LILLY’S LEGAL AND LIBRARY SERVICES EMPOWER TEAMS ACROSS THE DRUG DEVELOPMENT PIPELINE What role do the Library and Legal teams play in the drug development pipeline at Lilly? An import one – find out how. Sponsored by: CCC Whitepaper MEDICAL AFFAIRS METAMORPHOSIS VI: THE CHANGING FACE OF STAKEHOLDER ENGAGEMENT This paper focuses on stakeholder engagement and how Medical Affairs teams’ responsibilities, goals, tools, and techniques are changing. Sponsored by: Blue Matter, strategic consultants in the life sciences Research MAXIMIZING CLINICAL TRIAL SUCCESS Strategies for Optimal Site Selection and Feasibility Research in Novel Therapies and Geographies Sponsored by: H1 Whitepaper ECONSENT: FLEXIBLE CONSENT THROUGH ENABLING TECHNOLOGIES How can eConsent provide a more flexible approach to informed consent? Sponsored by: YPrime INDUSTRY EVENTS Drug Development Boot Camp® Spring 2024 In-Person April ‌10-11, ‌2024 UPCOMING FIERCE EVENTS 12-14 Jun Digital Pharma Engage San Diego, CA 13 Jun Fierce Biotech Next Gen Free Virtual Event 20-22 Jun Digital Pharma Innovation Week Free Virtual Event 22 Jun Fierce Leaders in Life Sciences Forum Free Virtual Event 18-19 Jul Pharma PR & Communications Summit July 18-19, 2023 | Jersey City, NJ View all events Brand Logo W Linkedin Logo @ 1IN Facebook LogoTwitter LogoYoutube Logo  Connect Advertise Contact Subscriptions Contact Support Our team Senior Editor: Annalee Armstrong Staff Writers: Max Bayer, Helen Floersh, Gabrielle Masson Contributing Writer: Nick Paul Taylor UK/EU Bureau Chief: James Waldron Editor-in-Chief: Ayla Ellison Senior Multimedia Producer: Teresa Carey Publisher: Rebecca Willumson Group Sales Director: Angelique Alcover This email was sent to [email protected] as part of the Fierce Biotech email list. f SRS RIS RO K %Jj L
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