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prosecution. Other restrictions may apply. Cash Value 1/10¢.
CBD stands for cannabidiol. It is one of the many chemical compounds found in hemp and marijuana plants. CBD oil is a supplement
that can be added to a variety of different products, such as lip balm, lotion, drinks, and gummies. CBD oil is created by
extracting cannabidiol from the flowers and buds of hemp or marijuana plants. The plant cannabis sativa can be classified as
either hemp or marijuana, depending on the amount of THC, the chemical that creates a high when consumed, in it. If the particular
sativa plant contains less than 0.3 percent THC, it is technically hemp. If the plant has more than 0.3 percent THC, it's
classified as marijuana. Hemp is generally used more for CBD extraction, as it contains more CBD and is legal in all 50 states.
But how is the CBD extracted from the plant? The process varies by CBD manufacturer. There are many ways to extract CBD from a
plant, and they vary in safety and efficiency. It's important to know the difference since how CBD is extracted affects the final
product's purity and efficacy. This article will explain the different methods of how CBD oil is made. If you'd like to learn more
about the business side of CBD, you can check out our article on how to start a cannabusiness. Carbon Dioxide One of the more
popular extraction methods for CBD oil uses carbon dioxide, or CO2. This system takes advantage of how CO2 can function as a gas,
solid, and liquid. Closed-loop extractors are most commonly used for CO2 extraction. The process starts with a solid piece of CO2
in a chamber that is then pumped into a second chamber containing the cannabis material. The second chamber is kept at such a
pressure that the CO2 stays in a liquid-like state and absorbs the plant's oils and flavors. Then, the CO2-cannabinoid mixture is
pumped into a third chamber where the CO2 returns to a gas state, leaving behind the plant's oil and flavors. CO2 extraction is
exact and can produce some of the purest cannabinoid extracts when done correctly. However, this is not always the case because of
the high cost of equipment and the steep learning curve. When this is done well, CO2 extracted CBD oil is some of the world's
purest, but there is ample room for error when done in less-than-optimal conditions. That potential for error is why subcritical
CO2 extraction is used mainly by more "boutique" CBD brands. Ethanol Ethanol extraction is another popular extraction process, as
it is safe, simple, and effective. In this method, high-grade grain alcohol (ethanol) is used as a solvent to separate CBD and
other cannabinoids from the plant itself. Ethanol extraction can be done under warm or cold conditions and is considered extremely
time-efficient compared to other CBD extraction processes like CO2 extraction. The CBD oil created with this method is often used
for vape pen cartridges and other products. However, this extraction method destroys the cannabis plant waxes, which may have
health benefits that some product-makers favor. Liquid Solvents The idea of using a liquid to absorb CBD oil from the cannabis
plant doesn't stop with CO2 or ethanol. Naturally liquid substances are also used, including butane, hexane, or isopropyl alcohol.
The process works much like the CO2 or ethanol extraction process, as a liquid solvent is run through decarboxylated hemp to
remove cannabinoids and terpenes. Liquid solvent extraction is a less expensive and easier way to extract CBD oil and is easy to
scale for commercial production, but it has its downsides. Not all solvents can remove all impurities, and the chlorophyll from
the plant may remain in the oil, giving it a greenish tinge and a bitter taste. A CBD manufacturer must adjust the process as
needed to avoid impurities. As many of the liquid solvents used are highly flammable, this method can be considered more dangerous
than others. Oil Infusion Oil infusion is one of the oldest techniques for extracting CBD oil, and many home growers and producers
still use this method today. It's one of the most straightforward ways, but it does come with some drawbacks. Before starting oil
infusion, the plant material must first be decarboxylated or heated to a specific temperature to activate the compounds. The plant
material is added to olive oil or a similar carrier oil and heated at 100 degrees Celsius for a couple of hours. The olive oil
can't evaporate out of the CBD oil, so one of the primary downsides is that a lot more oil is used compared to the amount of
liquid solvents used in their processes. Secondary Processes As some of the above processes result in impure CBD oil, many
manufacturers choose to use one or both of the following secondary processes in order to further purify their product.
Winterization Winterization is the secondary process of removing undesirable substances from the oil to result in pure CBD. After
the oil is extracted, it is combined with 200 proof alcohol and stirred vigorously until thoroughly mixed. The alcohol thins the
crude oil out, as the desirable parts of crude will go into solution with the alcohol while the unwanted parts will coagulate and
freeze, allowing them to be filtered out. The mixture is then placed in a deep freezer at below-zero temperatures. Once it has
time to freeze overnight, it looks cloudy and is ready for filtration. The filter removes the fats and other such materials. The
oil and alcohol mixture is placed in vessels that use paper filters. The actual CBD oil remains with the alcohol solution and
passes through the filter while the unwanted frozen parts are caught by it. When the oil is of the desired quality, the mixture
can be heated to alcohol's boiling point, which is lower than that of CBD oil, to boil off the alcohol. The alcohol evaporates,
and CBD oil is left behind. Distillation For further CBD oil refinement, it is run through a process called short path
distillation. This secondary takes advantage of the fact that different CBD oil compounds each have their own boiling point. Short
path distillation starts by slowly heating the CBD oil until the unnecessary substances such as terpenoids, flavonoids, and
contaminants, begin to boil off. Sometimes a vacuum is also used to separate the vapors with a lower boiling point. The vapors
formed travel through a distillation tube until they reach cooling coils, where they condense and drip down into a separate
collection container. The process continues until only pure CBD oil is left in the original container. Conclusion Outlined above
are the basics of what CBD is and how CBD is made. Following the manufacture of the oil itself also requires manufacturing of
delivery mechanisms, which include containers such as vials and bottles, to vape cartridges and other mechanisms. Of course there
is a lot more to the manufacturing process such as CBD product packaging. To find more information on domestic commercial and
industrial suppliers of custom manufacturing services and equipment on all levels of the supply chain, visit the Thomas Supplier
Discovery Platform, where you will find information on over 500,000 commercial and industrial suppliers.
HOW WILL CBD MAKE ME FEEL? The impact CBD has on the human body is, given the way we are mostly all made the same inside, similar
for many people. However, the dosage you take, the strain of hemp used in the product, how/where the product is grown, extraction
and other ingredients included, not to mention the reason you have chosen to take CBD products in the first place, all make for
unique experiences. As a very simple explanation, you can think of the core effect of CBD as being similar to that you experience
when you take something like Paracetamol (Acetaminophen). When it takes effect you experience the absence of symptoms and a return
back to a more ‘normal’ state - more ‘you’. First and foremost, legal, professionally made CBD products in the UK will not get you
high. There’s little to no THC present in CBD oil that is sold legally in this country - that’s the psychotropic compound commonly
associated with the heady, almost drunk feeling you can get from consuming marijuana. However, that being said, stronger doses of
CBD (1,000mg+, far more than would ever normally be consumed) may make you feel ever-so-slightly light headed, briefly, as it
works its way into your bloodstream and around the receptors in your body. This is nothing to be concerned about. In fact, this
sensation is mostly your own ‘bliss molecule’, the endocannabinoid called Anandamide, being allowed to flow freely as a result of
CBD binding to your CB1 and CB2 receptors which then changes the shape, blocking Anandamide’s usual spot, while inhibiting the
enzyme which would ordinarily break Anandamide down before it has a chance to get around. If THC is also present, this sits
tightly in those receptors so there’s no chance of Anandamide settling in, making for even more of that lovely stuff swimming
around your system. But this little ‘rush’ isn’t the case for everyone. In fact, those with acute pain, anxiety, sleep deprivation
(to name but a few) often find that all they feel is a sudden sense of equilibrium, perhaps manifested as pain reduction, a wash
of soothing calm, or an energy boost. Interestingly, the same goes for many people using medical marijuana for acute distress,
even with higher levels of THC present. Many experts have theorised that this feeling of restored balance may come from a
regulation of something dubbed an ‘endocannabinoid deficiency’ – an extremely common problem where our bodies have stopped
producing and delivering appropriate amounts of Anandamide and a wide variety of other endocannabinoids, resulting in troubles
with many cognitive and physiological processes, such as memory, pain, stress response, and appetite. A number of factors are
thought to cause endocannabinoid deficiency, such as lack of quality sleep, poor diet and chronic stress. CBD products simply help
your body return to centre. HOW CAN I START USING CBD IN THE MOST EFFECTIVE WAY? CBD oral drops The best way to consumer CBD is
often a personal choice. The most common way is to start with CBD oil drops, taken under the tongue. Simply place 4-5 drops under
your tongue and allow to absorb for 90 seconds before swallowing. It's really important to seek out high a quality product, from a
reputable brand where you can be assured that you're getting what's on the label. Ideally a broad spectrum CBD oil, rather than
one based on CBD isolate, so that you also get the benefit of the other minor cannabinoids and terpenes present in the cannabis
plant (hemp plant). Beware brands trying to pass off Hemp Oil as CBD Oil - they are not the same thing! You can read about the
Difference between Hemp Oil and CBD Oil here. KLORIS CBD are one of the most awarded CBD brands, with stringent quality control
and are available for next-day delivery from this website, found in leading health spas like Six Senses and Bvlgari and are one of
the only CBD oil brands to be recognised under the Medical Cannabis Clinicians Society Criteria For Excellence. HOW CAN CBD AFFECT
PEOPLE IN SO MANY DIFFERENT WAYS? Does it seem a little strange to you that some people use CBD to relax while others use it as a
pick-me-up? It’s certainly a very special property of CBD products and it comes down to two things: Cannabis is pleiotropic,
meaning it has many different effects through many molecular pathways and activates or binds to multiple receptors throughout the
body. Cannabis, although not officially labelled as an adaptogen, contains cannabinoids which work in a typically adaptogenic way,
adapting their function depending on what the body needs, be that physical, chemical or biological. Cannabis (and adaptogens such
as Ginseng and Reishi mushroom), bring the body back into balance, moderating stress response, lowering inflammation and even
enhancing mental performance. What’s more, they can possess opposing qualities, such as being stimulating and relaxing at the same
time. Whatever your body needs when the adaptogen gets involved. Amazing, huh? DOES CBD REALLY RELIEVE PAIN? CBD for pain relief
Cannabinoids on their own are endlessly captivating – there’s so much we have learned already, yet there is still so much more to
discover. But one thing we do know is that it’s how these cannabinoids work in synergy with each other (the entourage effect) and
with the endocannabinoid system (ECS) that gives the results people are raving about. Really, they’re just a gentle helping hand
to encourage your own body to function just as it should. The ECS spans the entire body. It’s considered to be one of the most
important and complex networks, alongside the Central Nervous System (CNS) and Immune System. The receptors that make up the ECS
have even been found within the CNS and Immune System and are now known to regulate mood, pain, inflammation, appetite,
coordination among many, many other functions./p> Because of this, plenty of CBD users have claimed that they find CBD to be
extremely effective when it comes to pain relief, when taken internally, as transdermal patches and also when applied topically,
as receptors are also found in almost every skin cell throughout all lipid layers. It’s not possible to make any hard claims as to
this yet though. IS CBD OIL ADDICTIVE? You may find that once you start taking CBD oil, the change to your body is so wonderful
that you’ll not want to be without it! But this isn’t because it’s addictive. It’s just a game-changer. At a molecular level CBD
is not in any way addictive and numerous studies have shown this to be the case. In contrast, evidence suggests that CBD may
actually help combat existing addiction to substances such as tobacco, alcohol and even opioids. One week-long 2013 study
published in the Addictive Behaviours journal found that participants given a CBD inhaler to use every time they felt the need to
smoke reduced their number of cigarettes by 40%, while those with the placebo showed no notable difference. Another 2019 study
published in the American Journal of Psychiatry observed the effects of treating long-term heroin users with CBD. The 42 subjects
were split into three groups, one had 400mg of CBD administered, the second were given 800mg and the third received a placebo. The
results showed that those who used CBD experienced significantly less cravings and anxiety induced by the drug cues. CAN I DRINK
ALCOHOL WHILE TAKING CBD? Mixing cannabis with alcohol is usually a no-no, as many a teenager will attest to, however, this is not
the case when it comes to low THC or THC free CBD products. Where marijuana with booze might leave you feeling very much worse for
wear, CBD is actually thought to have the opposite effect by soothing alcohol induced depression and anxiety for a far more
relaxed buzz. Better still, the negative side effects of drinking could be somewhat cushioned by including CBD in your tipple. One
2013 study in the journal of Pharmacology Biochemistry and Behaviour, found that CBD reduces the neurodegeneration drinking can
cause, while another 2014 study published in the journal of Free Radical Biology and Medicine revealed that CBD protects the liver
by inhibiting oxidative stress and increasing the destruction of damaged cells. This, blended with everything else CBD helps your
body do, could not only make for a more enjoyable night, but a more bearable morning after too. CAN I TAKE CBD WITH MEDICATION?
There is still so much to learn about CBD and this is one area that is crying out for attention - the reason for this being that
the potential CBD has for those on medication could possibly be great, or not good at all. Cannabidiol (and cannabis, including
THC and all other cannabinoids) has a fantastic safety record as a food supplement, even in high doses. Unlike many pharmaceutical
medications there’s no chance of serious harm if you take a little more than you mean to. However, some studies have indicated
that CBD has the ability to block a family of enzymes called cytochrome P450, which are responsible for metabolising (and
therefore eliminating) 70% to 80% of pharmaceutical drugs in the liver. If enough research is done and safety measures are put
into place, this could open up the possibility of patients being able to take much lower doses of their medication when used
alongside CBD oil. But it could also indicate build up of pharmaceutical chemicals in your system, which may end being very toxic.
Until we know more, it’s best to err on the side of caution. And of course, always consult a medical professional for their expert
advice. DOES CBD OIL HAVE ANY NEGATIVE SIDE EFFECTS? A huge and ever-increasing number of studies looking into cannabidiol are now
(thankfully and finally!) being published on a yearly basis, and the vast majority of them are pointing towards CBD being a pretty
amazing thing in almost all respects. But as this is still a relatively new science (the ECS was only discovered in the 90s after
all) and widespread use of concentrated CBD is a recent thing, we are always learning. So far, the World Health Organisation deems
CBD as perfectly safe, without risk of dependency or abuse and full of promise for a wide range of medical uses. The only clinical
trial showing negative side effects has been through using extremely high doses of Epidiolex, an FDA-approved CBD prescription
medication. This looked at daily doses equivalent to 1,360 mg (more than an entire bottle of most CBD products) and even that
exhibited mild symptoms such as dry mouth, decreased appetite and gastrointestinal distress. That being said, it is vitally
important to be wary of poor quality, unregulated CBD products. When purchasing CBD, always look for organic growing methods and
transparent lab reports to ensure you are only ever putting the very best ingredients into your body. HOW LONG WILL I FEEL THE
EFFECT OF CBD FOR? You're probably wondering how long does CBD last - this mostly depends on what form of CBD you take (i.e. oil,
capsules, vapes, edibles etc). Vaping or using cbd oil drops sublingually (under the tongue) ensures the CBD enters your
bloodstream fast, and you’ll start to feel the effects within 5-10 minutes. Capsules and edibles take much longer to get to work
(up to 90 minutes) and, due to having to go via your digestive system, will end up having lower bioavailability too (so you need
to take much more to have the same effect). But they’re great for a slow, steady, accumulative build up. Once CBD is in your
system, however it gets there, it will reach what’s known as ‘elimination half-life’ (the time it takes to reach half the dosage
in your body) in 18 to 32 hours. But you won’t feel it as strongly during this whole time as you do when it first gets going
(what’s called ‘active life’), even though those lovely cannabinoids will still be subtly working away. HOW CAN I MAKE SURE I GET
THE BEST CBD? Knowing which are the best CBD products to try can be a confusing task, but there are a few easy things to check:
Make sure the source of the CBD is clearly labelled as hemp, or Cannabis Sativa L. This form of the cannabis plant is naturally
low in THC and is the only legal source of CBD for non-medicinal products in the UK and Europe. Ingestible products like CBD oil
should ideally be made from broad spectrum CBD extract, meaning that there are other minor compounds present, as naturally found
in the hemp plant. There is growing evidence to suggest this more natural form is more beneficial than 'purified' CBD isolate.
Ensure that there are current laboratory analysis reports (sometimes called Certificates of Analysis, or COAs) available for your
products. These should show the levels of CBD, THC and other cannabinoids. If the certificates don't show the company name and a
batch number that matches your product, or are more than a year old, be wary. Organic is always better. Hemp plants are very good
at sucking up toxins from the soil. Look for well known third party accreditations, reviews and awards that show the brand is
legitimate.
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